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Botulinum toxin (Botox) is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. Botox Cosmetic is an injectable wrinkle muscle relaxer It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. Infection with the bacterium causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes.
Botox treatment is minimally invasive. It’s considered a safe, effective treatment for fine lines and wrinkles around the eyes. It can also be used on the forehead between the eyes.
Botox was originally FDA approved in 1989 for the treatment of blepharospasm and other eye muscle problems. In 2002, the FDA approved the use of Botox for cosmetic treatment for moderate to severe frown lines between the eyebrows. It was approved by the FDA for the treatment of wrinkles around the corners of the eyes (crow’s feet) in 2013.